Two of Nintendo's most anticipated games will be on show at this year's event and attendees will be able to go hands-on with a range of titles for both Switch and 3DS.
A special Nintendo 3DS XL Samus Edition releases alongside the game on 15 September.
Live presentations will also give detailed looks at previously announced titles for Nintendo Switch and Nintendo 3DS, such as Fire Emblem Warriors and Xenoblade Chronicles 2.
Visitors can get their hands on Switch titles Super Mario Odyssey, Pokken Tournament DX, Fire Emblem Warriors, Mario + Rabbids Kingdom Battle, plus the recently released ARMS and Splatoon 2.
Whilst the 3DS games on offer include Mario & Luigi: Superstar Saga + Bowser's Minions, Monster Hunter Stories and Metroid: Samus Returns.
Looking forward to Gamescom? Let us know what you'd like to see below or over in the forums.